Hyperinsulinism

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What is Hyperinsulinism?

Hyperinsulinism, also known as Congenital Hyperinsulinism (CHI), is a disorder where the pancreas produces excessive insulin, even when blood sugar levels are already low. Since insulin lowers blood glucose, this leads to repeated episodes of hypoglycemia, which can be life-threatening if not managed quickly and effectively.

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Causes and Types

Hyperinsulinism may be:

  • Congenital (genetic mutations) – most common in newborns and infants

  • Transient – due to birth stress, diabetic mothers, or perinatal asphyxia

  • Focal or diffuse – affecting one area or the entire pancreas

Symptoms of Hyperinsulinism

Early signs, especially in newborns and infants, may include:

  • Jitteriness or tremors

  • Poor feeding or vomiting

  • Excessive sleepiness or lethargy

  • Seizures

  • Loss of consciousness

  • Low body temperature

Prompt detection is critical to prevent permanent neurological damage.

Diagnosis and Treatment in Ghaziabad

Diagnostic tools include:

  • Frequent blood glucose monitoring

  • Insulin and C-peptide levels during hypoglycemia

  • Genetic testing (to determine focal or diffuse disease)

  • PET scan or 18F-DOPA scan to localize the insulin-producing lesion

Treatment options:

  • Frequent feeding and IV glucose for immediate sugar balance

  • Medications such as Diazoxide or Octreotide

  • Surgical treatment:

    • Partial pancreatectomy for focal lesions

    • Near-total pancreatectomy for diffuse disease unresponsive to medication

Long-term monitoring of blood sugar levels and developmental milestones is essential.

Why Choose Us?

  • Expert pediatric endocrinologists and surgeons

  • NICU and advanced imaging support

  • Minimally invasive surgical options

  • Comprehensive long-term care and family education in Ghaziabad

If your newborn or child shows signs of unexplained low blood sugar or seizures, Hyperinsulinism could be the cause. Contact us today for immediate evaluation and advanced pediatric endocrine care in Ghaziabad. Early diagnosis can protect your child’s brain and ensure a healthier future.